: 23214-92-8) Manus Aktteva Biopharma LLP is an ISO 9001:2015 Certified Global Supplier based in India for the product Doxorubicin, 23214-92-8. PDF Doxorubicin liposomal (Doxil®, Lipodox®) Encapsula NanoSciences is the formulator and manufacturer of Clodronate liposomes (Clodrosome ® ), control liposomes for Clodrosome (Encapsome ® ), Doxorubicin liposomes (Doxosome ™ ), surface active liposomes for antibody and peptide conjugation (Immunosome ® ), DNA and RNA liposomes (Genesome ® ), fluorescent liposomes (Fluoroliposome . Xi 'an Quanao Biotech Co., Ltd. with 10 years experience in plant extract filed. Doxorubicin is used in combination with other medications to treat certain types of bladder, breast, lung, stomach, and ovarian cancer; Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (cancer that begins in the cells of the immune system); and certain types of leukemia (cancer of the white blood cells), including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia . Adriamycin® (Doxorubicin HCL) - GlobalRPH High quality Doxorubicin hydrochloride Powder Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal extracts. The doxorubicin shortage is due in part to the fact that one of three companies that make the drug, TEVA Pharmaceuticals, was told earlier this year to stop manufacturing the drug by the FDA. Doxorubicin | CancerQuest Doxorubicin . Manufacturer Link. In this study, the goal was to identify the histopathological changes of doxorubicin on the kidney of male rats weighing 200-225g, and the doxorubicin injected intraperitoneally. Trumac Healthcare is one of the leading Doxorubicin Liposomal Injection Manufacturers Suppliers all over India. Doxorubicin | Manufacturers | Suppliers | India Doxorubicin | CAS:23214-92-8 | Topo II inhibitor ... Doxorubicin Hydrochloride Injection, USP, is a sterile parenteral, isotonic solution. Pharmaceutical 59676096001 Two different mechanisms, (i) intercalation of doxorubicin into DNA . 3. Doxorubicin Manufacturers, Doxorubicin Suppliers ... Doxorubicin Hcl Manufacturer, Doxorubicin Hcl Supplier ... Melon GlobalCare export Doxorubicin (Liposomal) to Russia, Australia, Brazil, UAE and many other countries. Chapter 4, the Liposomal Doxorubicin breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2015 to 2020. Generic drug Doxorubicin available with manufacturer details. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Ask your doctor any questions that you may have about doxorubicin. Doxorubicin, the active substance in Caelyx pegylated liposomal, is a cytotoxic medicine that belongs to the group 'anthracyclines'. Order now can get a discount! in vivo. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. Drinking extra fluids while you are using doxorubicin is recommended. Doxorubicin is administered via an intravenous (IV) injection through a central line or a peripheral venous line, and the drug is given over several minutes. It is used in the treatment of some kinds of cancer. Not for human use. Products are for laboratory research use only. Both doxorubicin and trastuzumab deruxtecan can increase the risk of myelosuppression. Find here huge list of doxorubicin injection manufacturers, doxorubicin injection suppliers, doxorubicin injection exporters along with manufacturing companies from India. 6. [1] It is an anthracycline antibiotic. Fertility: Treatment with doxorubicin may produce gonadal suppression, resulting in amenorrhea or azoospermia.11 Pregnancy: Doxorubicin is classed as FDA Pregnancy Category D.24 There is positive evidence of human fetal risk, Global Doxorubicin Market Share, by Region, 2017 (%) Source: MRFR Analysis The Americas are expected to dominate the doxorubicin market owing to the growing pool of cancer patients associated with increasing elderly population, strong presence of major manufacturers in the region, and adoption of advanced healthcare facilities coupled with . Doxorubicin is predicted to increase the risk of cardiotoxicity when given with trastuzumab deruxtecan. Doxorubicin Hydrochloride Injection/for Injection is an anthracycline topoisomerase inhibitor indicated: as a component of multiagent adjuvant chemotherapy for treatment of women with axillary lymph node involvement following resection of primary breast cancer ().for the treatment of: acute lymphoblastic leukemia, acute myeloblastic leukemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic . Judson I, Radford JA, Harris M, et al. Founded in 2012 by Prof. Chezy Barenholz (co-inventor of Doxil® - Doxorubicin-HCl Liposomal Injection) Lead product LC101 (Doxorubicin-HCl Liposomal Injection) approved by FDA for treatment of Ovarian Cancer, Multiple Myeloma and AIDS-related Kaposi's Sarcoma. The rats were classified into two main . For the full list of excipients, see Section 6.1 List of excipients. Getwell Pharmaceuticals is a leading manufacturer and supplier of Pegylated Liposomal Doxorubicin Injection: I-Dox at a cost effective price in India. It is an anti-cancer medication used to harm cancer cells & kills them. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Doxorubicin Hydrochloride for Injection, USP, is a sterile red-orange lyophilized powder. It is used: After surgery to remove the primary tumor in women whose cancer has spread to the lymph nodes under the arm. View All Manufacturers & Suppliers of Doxorubicin API with Drug Master Files (DMF), CEP/COS, Japanese DMFs, Written Confirmation (WC) details listed on PharmaCompass.com If stored at 25 ° C in the dark in 5% glucose, pH 4.7 (or 3.3% glucose + 0.3% sodium chloride, pH 4.4), solutions were stable (5% or less change) for at least 4 weeks. pegylated liposomal doxorubicin hydrochloride is a A liposome-encapsulated form of the hydrochloride salt of the anthracycline antineoplastic antibiotic doxorubicin. Active: Doxorubicin hydrochloride . Doxorubicin hydrochloride is subject to light degradation at <0.5 mg/mL, with considerable loss of bioactivity. Injection, solution, 2mg/mL. Our Doxorubicin is confirmed by NMR. Doxorubicin hydrochloride injection is indicated in the treatment of neoplastic conditions such as acute myeloblastic and lymphoblastic leukemia, soft tissue and osteogenic sarcomas, breast carcinoma, ovarian carcinoma, testicular carcinoma, thyroid carcinoma, squamous cell carcinoma, lymphomas, and bronchogenic carcinoma. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Doxorubicin is one of the most effective chemotherapy drugs used against solid tumors in the treatment of several cancer types. in vivo. BioCrick is a famous high-purity reference standards manufacturer. PHARMACEUTICAL FORM There is no pill form of Doxorubicin. Melon GlobalCare export Doxorubicin to Russia, Australia, Brazil, UAE and many more countries. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Find here Doxorubicin Hydrochloride Injection, Doxorubicin Injection manufacturers & OEM manufacturers India. It is used in the treatment of some kinds of cancer. Doxorubicin (Adriamycin) HCl(25316-40-9) Reference standards for Pharmacological research. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Trade name. The study is loaded with various exhibits, and advance insights related to returns, amount, and uncover, with provincial and worldwide economy forecasts.Doxorubicin market report is the . : 25316-40-9) Manus Aktteva Biopharma LLP is an ISO 9001:2015 Certified Global Supplier based in India for the product Doxorubicin hydrochloride, 25316-40-9. This competition landscape shows a view of. Click on the desired brand to find out the drug price or cost of the drug. 7. We offer the product Doxorubicin hydrochloride, 25316-40-9 from our manufacturer / supplier / principals for your Research and Development / Evaluation or . [1] Ann Oncol. chromosome tests. Currently in late-stage clinical trials, aldoxorubicin appears to overcome the key limitations of doxorubicin, including cumulative dose restrictions. Our Doxorubicin (Adriamycin) HCl is confirmed by NMR. Doxorubicin Market Size 2021 with Leading Countries, Industry Share, Top Key Manufacturer, Revenue, Business Boosting Strategies, CAGR Status with 3.77 % Growth Opportunities and Forecast 2027 DOXOrubicin . It interferes with the DNA in cells, preventing them from making more copies of DNA and making proteins. The lymphatic system is a large network of vessels that carry fluid and cells of the immune system . This means that cancer cells cannot divide and eventually die. The use of doxorubicin is, however, associated with severe cardiotoxicity, often resulting in early discontinuation of the treatment. Doxorubicin Hydrochloride Injection, USP is available as: It is used with other drugs. WHO:GMP Certified Third Party Contract Manufacturing also available. caesius. This medicine is used to treat many kinds of cancer like Kaposi's sarcoma, multiple myeloma, and ovarian cancer. Doxorubicin is given by injection into a vein.. Common side effects include hair loss, bone marrow suppression . Doxorubicin (Liposomal) bulk exporter, Lipodox 10mg Injection third contract manufacturer from India. Doxorubicin may cause heart muscle damage that may lead to heart failure, which is a condition in which the heart does not pump well. Medac GmbH. Doxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. Doxotero contains Doxorubicin. Doxorubicin is a semi-synthesized anticancer agent derived from bacterial culture. Doxorubicin hydrochloride (CAS No. Each 10 ml & 30 ml vials contains 20 mg & 50 mg of Doxorubicin HCl respectively at a concentration of 2 mg/ml. It is be. BioCrick. Doxorubicin hydrochloride injection is indicated in the treatment of neoplastic conditions such as acute myeloblastic and lymphoblastic leukemia, soft tissue and osteogenic sarcomas, breast carcinoma, ovarian carcinoma, testicular carcinoma, thyroid carcinoma, squamous cell carcinoma, lymphomas, and bronchogenic carcinoma. Secured FDA accredited, cGMP manufacturing facility to support commercial launch. Breast cancer. Hypersensitivity to doxorubicin, other anthracyclines or anthracenediones eg, epirubicin, daunorubicin, mitoxantrone or mitomycin C. Marked persistent myelosuppression induced by previous treatment w/ other antitumor agents or radiotherapy (baseline neutrophil count <1,500 cells/mm 3).Severe hepatic impairment, myocardial insufficiency & arrhythmias; recent MI; history of severe cardiac disease. Doxorubicin Market - Analysis and Insights: The global Doxorubicin market was valued at 860.92 Million USD in 2020 and will grow with a CAGR of 3.77% from 2020 to 2027. Doxorubicin is usually administered as an injection at your doctor's office, hospital, or clinic. Aldoxorubicin is a rationally-engineered cytotoxic which delivers well-established anti-cancer agent, doxorubicin, into the tumor. We have a range of complex generics and drug delivery based formulations. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin may also inhibit polymerase activity, affect regulation of gene expression and... 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